A 1959 graduate of Harvard Medical School, Dr. Epstein moved to San Francisco to join the UCSF Cancer Research Institute, initially as a research physician and later becoming Associate Director. She was a pioneer in the research of interferons, and together with husband Dr. Charles Epstein, developed the first mouse model for Down syndrome. Her many honors included a National Institutes of Health MERIT award, the Lifetime Achievement in Research Award from the International Society for Interferon and Cytokine Research, and an honorary Doctor of Science Degree.
Above all, Dr. Epstein was a warm and loving person who brought a spirit of grace to every aspect of her life. She will be missed. The Epstein Family legacy is honored by The Charles J. and Lois B. Epstein Visiting Professorship, which provides for an annual UC lectureship by a globally renowned human geneticist.