John Witte, PhD

Professor of Epidemiology and Biostatistics and of Urology Co-Leader, Program in Cancer Genetics, Helen Diller Cancer Center


Dr. Witte’s research constitutes applied and methodologic genetic epidemiology, with the aim of deciphering the mechanisms underlying complex diseases. His applied work is primarily focused on prostate cancer, while much of his methodologic work is on association studies and hierarchical modeling. Dr. Witte initiated a series of prostate cancer genetic epidemiology studies, which have had numerous successes toward sorting out the genetic basis of this disease. In particular, using a combination of genome-wide scan, allelic imbalance, and association studies, Dr. Witte and colleagues have isolated distinct chromosomal regions that appear to harbor genes that cause prostate cancer.