Seymour Packman, MD

Professor Emeritus of Pediatrics

Dr. Packman’s recent emphasis has been on clinical investigation and academic program development, embodied in the formation of the Neurometabolic Program, and the Lysosomal Disease Center. Current focus in clinical investigations, under the auspices of these programs, is on the natural history and disease mechanisms of lysosomal storage disorders — in particular, the pathogenesis of neurologic manifestations in Fabry disease. He has maintained a laboratory effort in experimental studies directed towards disease mechanisms in genetic disorders of micronutrient metabolism. Current experimental efforts are being developed to identify modifier genes in galactosemia, using the galactosemic mouse oocyte as a model system.