The UCSF Institute for Human Genetics (IHG) serves as the hub for all activities in human genetics at the University of California, San Francisco.
OUR MISSION is to create an exciting, productive, and collaborative environment for research, training, and clinical application in human genetics.
Our faculty span all four schools (Dentistry, Medicine, Nursing, Pharmacy), and many departments within those schools, reflecting the broad importance of human genetics both in basic scientific research and in modern day health care. The sequencing of the human genome, accompanied in recent years with the dramatic reduction in cost for obtaining an individual’s genome sequence, augurs a new era in translational human genetics, impacting not only rare, Mendelian diseases but effectively all diseases affecting the human population. The IHG and its members intend to be in the forefront of these transformational developments.
The IHG is proud to announce that Louis Ptáček will receive the American Society for Clinical Investigation’s Stanley J. Korsmeyer Award and Ophir Klein will be awarded the E Mead Johnson Award from the Society for Pediatric Research.
Louis Ptáček, MD, PhD is a pioneer in the field of “channelopathies”— episodic and electrical disorders of muscle, heart and brain. He cloned the genes for all the familial periodic paralyses and proposed these rare muscle disorders as a model for pathogenesis of cardiac arrhythmias, epilepsy and migraine. This work has already led to better diagnosis and treatment of patients.
Ophir Klein, MD, PhD has worked at the interface of genetics, development, and evolutionary biology to advance our understanding of stem and progenitor cells. He has used the continuously-growing rodent incisor as a novel system for investigating mammalian stem cells, and his group has also made contributions to the biology of renewal in the intestine, tongue, and other organs.
Louis Ptáček will receive his award at the annual ASCI Meeting in April. Ophir Klein will receive his award at the annual Pediatric Academic Societies meeting in April.