The UCSF Institute for Human Genetics (IHG) serves as the hub for all activities in human genetics at the University of California, San Francisco.

OUR MISSION is to create an exciting, productive, and collaborative environment for research, training, and clinical application in human genetics.

Our faculty span all four schools (Dentistry, Medicine, Nursing, Pharmacy), and many departments within those schools, reflecting the broad importance of human genetics both in basic scientific research and in modern day health care. The sequencing of the human genome, accompanied in recent years with the dramatic reduction in cost for obtaining an individual’s genome sequence, augurs a new era in translational human genetics, impacting not only rare, Mendelian diseases but effectively all diseases affecting the human population. The IHG and its members intend to be in the forefront of these transformational developments.


In Fond Memory and Celebration of Lois Epstein

Lois Epstein, MD, DScDr. Lois Barth Epstein, a beloved member of the UCSF Human Genetics community, passed away on February 6, 2015 after a short illness.

A 1959 graduate of Harvard Medical School, Dr. Epstein moved to San Francisco to join the UCSF Cancer Research Institute, initially as a research physician and later becoming Associate Director. She was a pioneer in the research of interferons, and together with husband Dr. Charles Epstein, developed the first mouse model for Down syndrome. Her many honors included a National Institutes of Health MERIT award, the Lifetime Achievement in Research Award from the International Society for Interferon and Cytokine Research, and an honorary Doctor of Science Degree.

Above all, Dr. Epstein was a warm and loving person who brought a spirit of grace to every aspect of her life. She will be missed. The Epstein Family legacy is honored by The Charles J. and Lois B. Epstein Visiting Professorship, which provides for an annual UC lectureship by a globally renowned human geneticist.

Obituary in Marin Independent Journal

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