The UCSF Institute for Human Genetics (IHG) serves as the hub for all activities in human genetics at the University of California, San Francisco.
OUR MISSION is to create an exciting, productive, and collaborative environment for research, training, and clinical application in human genetics.
Our faculty span all four schools (Dentistry, Medicine, Nursing, Pharmacy), and many departments within those schools, reflecting the broad importance of human genetics both in basic scientific research and in modern day health care. The sequencing of the human genome, accompanied in recent years with the dramatic reduction in cost for obtaining an individual’s genome sequence, augurs a new era in translational human genetics, impacting not only rare, Mendelian diseases but effectively all diseases affecting the human population. The IHG and its members intend to be in the forefront of these transformational developments.
Yin Shen was recruited to the Institute for Human Genetics from Dr. Bing Ren’s lab at Ludwig Institute for Cancer Research at UC San Diego in La Jolla, CA, where she led the genomic functional characterization effort in the mouse ENCODE project. She earned her PhD from UCLA, where she studied epigenetics and gene regulation, utilizing cutting-edge genetics, genomics and stem cell technologies.
Chun (Jimmie) Ye received his PhD in Bioinformatics and Systems Biology at UC San Diego/UCLA, where he developed a number of statistical methods for identifying and interpreting genetic loci associated with gene expression (eQTL). As a postdoc at the Broad Institute under Aviv Regev, Jimmie led a team of computational and experimental biologists to study the role of genetic variation in the response of immune cells to cytokines and/or pathogens.
Yin and Jimmie are settling beautifully into their respective labs on the 9th floor of UCSF Parnassus. Please stop by to say hello, and join us in wishing them great success at UCSF.