Chris Hsiung, MD, PhD

Assistant Professor Institute for Human Genetics and Dept. of Surgery

Dr. Chris Hsiung, originally from Taipei and a long-time Bay Area resident, brings a wealth of experience and a remarkable track record in research. Chris conducted his postdoctoral research while serving as an Instructor in the Physician Scientist Incubator in the Department of Pathology at Stanford University. Chris conducted his postdoctoral research while appointed as Instructor in the Physician Scientist Incubator in the Department of Pathology at Stanford University. This program supported Chris to conduct his postdoctoral research with any institution in the San Francisco Bay Area, enabling Chris to join Luke Gilbert's lab as a Visiting Scholar at the Arc Institute and UCSF. There, Chris developed a CRISPR functional genomics platform and a conceptual framework for exploring higher-order combinatorial chromatin perturbations. Prior to this, Chris completed his Clinical Pathology residency at Stanford University and MD-PhD training at the University of Pennsylvania, co-advised by Arjun Raj and Gerd Blobel. During his PhD, Chris contributed to knowledge of genome regulation during cell division through single-molecule RNA imaging and epigenomics approaches. In his new role with us, Chris will establish a research program that innovates at the forefront of synthetic gene regulation, combinatorial genetics, and functional genomics of tissue biology.

The Hsiung Lab is interested in 1) understanding and engineering transcriptional regulation using synthetic biology and functional genomics approaches, 2) efficient approaches to exploring numerous combinatorial genetic perturbations, 3) applying those approaches to understand and engineer emergent properties of tissues, including tissue responses to injury and immune recognition of cancer.