Dr. State focuses on gene discovery as a means to elaborate the molecular and cellular mechanisms underlying childhood onset neuropsychiatry disorders, with a particular focus on autism, Tourette disorder and childhood onset schizophrenia. His lab leverages both traditional mapping techniques, including in consanguineous families, as well as high throughput genomic methods in large patient cohorts. His lab is also currently working on generating and integrating data on gene regulation and expression to seek points of mechanistic, spatial and temporal convergence among divergent genes contributing to a common psychiatric presentation.