Michael T. McManus, PhD

Vincent and Stella Coates Endowed Chair Associate Professor of Microbiology and Immunology Director, UCSF Keck Center for Noncoding RNAs


Dr. McManus studies biological processes relating to mammalian gene expression with high-throughput approaches, analyzing hundreds of thousands to millions of experiments at once, using complex libraries coupled to deep sequencing. The systems span from cell culture to in vivo models or a broad array of disease relevant tissues. From cancer to diabetes, his laboratory develops novel technologies to understand how genes are regulated and how they function in cells, including the systematic analysis of pathways and how genes interact in development and disease. A major focus is to uncover roles for noncoding RNAs, the veritable Dark Matter of the genome.