Nadav Ahituv, PhD


Dr. Ahituv’s research focuses on understanding the role of regulatory sequences in human biology and disease. Through a combination of comparative genomic strategies, regulatory element analysis, human patient samples, and mouse and fish genetic engineering technologies, he is working to elucidate mechanisms whereby genetic variation within these sequences lead to changes in human phenotypes. The research focuses on three clinically relevant phenotypic categories: monogenic disease, using limb malformations as a model; complex disease, analyzing how nucleotide changes in regulatory sequences contribute to obesity; and pharmacogenomics, characterizing how genetic differences in regulatory sequences lead to clinical variation in response to drugs.